Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50021625
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST-tagged SOS1 (564 to 1049 residues)/N-terminal his6-tagged KRAS (unknown origin) protein-protein interaction incubated fo...More data for this Ligand-Target Pair
TargetSon of sevenless homolog 1(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataKd: 9.70nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
