Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50022382
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataEC50:  1.79E+3nMAssay Description:Activation of N-terminal His-tagged recombinant human SIRT1 (193 to end residues) expressed in baculovirus infected Sf9 insect cells incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50241453(gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of AMC-conjugated recombinant human SIRT2 ( 317 to 320 residues) using sirtuin as substrate incubated for 45 mins by fluorescence based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of SIRT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50241453(gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of AMC-conjugated recombinant human SIRT1 (379 to 382 residues) using sirtuin as substrate incubated for 45 mins by fluorescence based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50241453(gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of AMC-conjugated recombinant human SIRT3 ( 317 to 320 residues) using sirtuin as substrate incubated for 45 mins by fluorescence based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed