Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50021649
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to human mPGES-2 (1 to 87 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50248021(CHEBI:63918 | Arsumax | Artesunate)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50643111(CHEMBL4857828)
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50248200(CHEBI:195280 | Artemether | Artemetheri)
Affinity DataIC50: 7.20E+3nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of heme-free recombinant mPGES-2 (unknown origin) pre-incubated with compound for 15 mins followed by PGH2 addition measured after 60 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 8.80E+3nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of heme-free recombinant mPGES-2 (unknown origin) pre-incubated with compound for 15 mins followed by PGH2 addition measured after 30 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50578409(CHEMBL307261)
Affinity DataIC50: 9.60E+3nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of heme-free recombinant mPGES-2 (unknown origin) pre-incubated with compound for 15 mins followed by PGH2 addition measured after 5 min b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of heme-free recombinant mPGES-2 (unknown origin) pre-incubated with compound for 15 mins followed by PGH2 addition measured after 10 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of heme-free recombinant mPGES-2 (unknown origin) pre-incubated with compound for 15 mins followed by PGH2 addition measured after 1 min b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50643112(CHEMBL5564353)
Affinity DataIC50: 1.12E+4nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50643113(CHEMBL4065591)
Affinity DataIC50: 2.02E+4nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50643114(CHEMBL5575055)
Affinity DataIC50: 3.55E+4nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin E synthase 2(Human)
Changshu Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50643110(DEOXYARTEMISININ)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of ART-P1 from heme-free recombinant mPGES-2 (unknown origin) assessed as inhibition of ART-P1 binding to mPGES-2 incubated for 1 hr fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed