Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50021443
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  38nMAssay Description:Binding affinity to SARS-CoV-2 Main protease assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetInterleukin-1 beta(Human)TBA
LigandPNGBDBM50640747(CHEMBL5567461)
Affinity DataKd:  40nMAssay Description:Binding affinity to Interleukin-1beta (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50640744(CHEMBL5574691)
Affinity DataIC50: 150nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Ra pantothenate synthetaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640745(CHEMBL5422554)
Affinity DataKd:  170nMAssay Description:Binding affinity to human recombinant N-terminal His-tagged TEAD1 (residues 209 to 424) expressed in Escherichia coli BL21 (DE3) assessed as dissocia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50640743(CHEMBL5590006)
Affinity DataIC50: 340nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Ra pantothenate synthetaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640741(CHEMBL5197731)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to human recombinant flag His-tagged PRMT5 ( 1 to 637 residues) expressed in HEK293 cells assessed as dissociation constant by SPR a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50640740(CHEMBL5555466)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to SARS-CoV-2 Main protease assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetInterleukin-1 beta(Human)TBA
LigandPNGBDBM50640746(CHEMBL5567114)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to Interleukin-1beta (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640742(CHEMBL5169665)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to human recombinant flag His-tagged PRMT5 ( 1 to 637 residues) expressed in HEK293 cells assessed as dissociation constant by SPR a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataKd:  7.30E+4nMAssay Description:Binding affinity to human recombinant N-terminal His-tagged TEAD2 (residues 209 to 424) expressed in Escherichia coli BL21 (DE3) assessed as dissocia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)