Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50021330
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639629(CHEMBL5560834)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H23 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639630(CHEMBL5564352)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H23 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639628(CHEMBL5568016)
Affinity DataIC50: 3nMAssay Description:Inhibition of GDP-bound KRAS G12C mutant in human MIA PaCa-2 cells incubated for 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639630(CHEMBL5564352)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H2030 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639627(CHEMBL5561896)
Affinity DataIC50: 5nMAssay Description:Inhibition of GDP-bound KRAS G12C mutant in human MIA PaCa-2 cells incubated for 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639631(CHEMBL5562104)
Affinity DataIC50: 6nMAssay Description:Inhibition of KRAS G12C mutant in human HCC1171 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639629(CHEMBL5560834)
Affinity DataEC50: >10nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H2030 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639631(CHEMBL5562104)
Affinity DataIC50: 10nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639625(CHEMBL5565693)
Affinity DataIC50: 60nMAssay Description:Inhibition of KRAS G12C mutant in human MIA PaCa-2 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639625(CHEMBL5565693)
Affinity DataIC50: 64nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639626(CHEMBL5531972)
Affinity DataIC50: 68nMAssay Description:Inhibition of KRAS G12C mutant in human MIA PaCa-2 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639626(CHEMBL5531972)
Affinity DataIC50: 102nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells measured after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed