Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50021456
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to BTK (unknown origin) assessed as inhibition constant measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of BTK (unknown origin) measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640859(CHEMBL5583871)
Affinity DataKi:  50nMAssay Description:Binding affinity to BTK (unknown origin) assessed as inhibition constant measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 89nMAssay Description:Inhibition of CRBN (unknown origin) measured after 60 mins incubation by BMG readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640859(CHEMBL5583871)
Affinity DataIC50: 96nMAssay Description:Inhibition of BTK (unknown origin) measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640860(CHEMBL5583805)
Affinity DataKi:  152nMAssay Description:Binding affinity to BTK (unknown origin) assessed as inhibition constant measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640860(CHEMBL5583805)
Affinity DataIC50: 248nMAssay Description:Inhibition of CRBN (unknown origin) measured after 60 mins incubation by BMG readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640859(CHEMBL5583871)
Affinity DataIC50: 285nMAssay Description:Inhibition of CRBN (unknown origin) measured after 60 mins incubation by BMG readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50640860(CHEMBL5583805)
Affinity DataIC50: 299nMAssay Description:Inhibition of BTK (unknown origin) measured after 60 mins incubation by microtiter-plate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed