Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50021332
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50233715(5-cyano-N-[4-(4-methylpiperazin-1-yl)-2-piperidin-...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50639633(CHEMBL5561172)
Affinity DataIC50: 6nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50255811(4-(2,4-difluorophenylamino)-7-ethoxy-6-(4-methylpi...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50255811(4-(2,4-difluorophenylamino)-7-ethoxy-6-(4-methylpi...)
Affinity DataKi:  8nMAssay Description:Binding affinity to CSF1R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50639632(CHEMBL5562279)
Affinity DataIC50: 10nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50532181(CHEMBL4474690)
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50639635(CHEMBL5558643)
Affinity DataKd:  16nMAssay Description:Binding affinity to human CSF1R assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50639634(CHEMBL5563216)
Affinity DataKd:  26nMAssay Description:Binding affinity to human CSF1R assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Graphic Era Hill University

Curated by ChEMBL
LigandPNGBDBM50639632(CHEMBL5562279)
Affinity DataKd:  36nMAssay Description:Binding affinity to TRKB (unknown origin) receptor assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed