Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50021024
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM311267(US10155760, Example 123 | (S)-1-((2′,6-bis(d...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 4nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50573690(CHEMBL4855590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50511397(CHEMBL4452939)
Affinity DataKi:  9.10nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636103(CHEMBL5557266)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50573688(CHEMBL4127773 | US20250270222, Compound LP-935509)
Affinity DataIC50: 10nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  11nMAssay Description:Binding affinity to AAK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636098(CHEMBL5564665)
Affinity DataIC50: 11nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636098(CHEMBL5564665)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50573682(CHEMBL4872886)
Affinity DataIC50: 12nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636100(CHEMBL5560434)
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636099(CHEMBL5542596)
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636102(CHEMBL5555032)
Affinity DataIC50: 36nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636118(CHEMBL5559910)
Affinity DataIC50: 44nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636101(CHEMBL5560369)
Affinity DataIC50: 48nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636116(CHEMBL5557141)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636109(CHEMBL5561202)
Affinity DataIC50: 54nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50273541(N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...)
Affinity DataIC50: 58nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50273541(N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...)
Affinity DataIC50: 58nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636112(CHEMBL5556790)
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636105(CHEMBL5561763)
Affinity DataIC50: 75nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 77nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636111(CHEMBL5566377)
Affinity DataIC50: 82nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636106(CHEMBL5564289)
Affinity DataIC50: 97nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636108(CHEMBL5561927)
Affinity DataIC50: 104nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636113(CHEMBL5566931)
Affinity DataIC50: 119nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50273541(N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...)
Affinity DataKd:  120nMAssay Description:Binding affinity to AAK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636119(CHEMBL5542834)
Affinity DataIC50: 155nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636107(CHEMBL5556067)
Affinity DataIC50: 155nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636110(CHEMBL5517717)
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636117(CHEMBL5560803)
Affinity DataIC50: 225nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50511397(CHEMBL4452939)
Affinity DataIC50: 296nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636114(CHEMBL5518125)
Affinity DataIC50: 406nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636104(CHEMBL5517817)
Affinity DataIC50: 500nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50636115(CHEMBL5567875)
Affinity DataIC50: 500nMAssay Description:Inhibition of GST-tagged recombinant human AAK1 (1 to 510 residues) expressed in insect cells using Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed