Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50021162
LigandPNGBDBM50055150(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of rat steroid 5-alpha-reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50615657(CHEMBL4099342)
Affinity DataIC50: 1.90nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hr by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50149341(8-Bromo-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]q...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human steroid 5-alpha-reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50149339(4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human steroid 5-alpha-reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50149327(4-Methyl-8-((E)-styryl)-1,2,5,6-tetrahydro-pyrido[...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human steroid 5-alpha-reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 41nMAssay Description:Inhibition of steroid 5-alpha-reductase 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50092492(4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...)
Affinity DataIC50: 41nMAssay Description:Inhibition of steroid 5-alpha-reductase 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50050086(US9216988, 55 | CHEMBL3317836)
Affinity DataIC50: 46nMAssay Description:Inhibition of RORgammat (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50569895(CHEMBL4862887 | US12145923, Compound C10)
Affinity DataIC50: 140nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50637612(CHEMBL4172726)
Affinity DataIC50: 250nMAssay Description:Inhibition of RORgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50569910(CHEMBL4848137)
Affinity DataIC50: 360nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50527953(CHEMBL4541672)
Affinity DataIC50: 4.70E+3nMAssay Description:Antagonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed