Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50020903
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148781BDBM50148781(CHEMBL3770903)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148781BDBM50148781(CHEMBL3770903)
Affinity DataIC50: 400nMAssay Description:Inhibition of human SIRT2 (25 to 389 residues) expressed in Escherichia coli BL21(DE3)Codonplus RIPL cells using Z-Lys(Acetyl)-AMC as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634710BDBM50634710(CHEMBL5555254)
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634700BDBM50634700(CHEMBL5518043)
Affinity DataIC50: 7.61E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634701BDBM50634701(CHEMBL5556453)
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634713BDBM50634713(CHEMBL5557521)
Affinity DataIC50: 8.63E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634703BDBM50634703(CHEMBL5542326)
Affinity DataIC50: 9.91E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634712BDBM50634712(CHEMBL5557139)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634709BDBM50634709(CHEMBL5559510)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634705BDBM50634705(CHEMBL5542871)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634706BDBM50634706(CHEMBL5557325)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634702BDBM50634702(CHEMBL5505900)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634707BDBM50634707(CHEMBL5556326)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634704BDBM50634704(CHEMBL5558060)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634714BDBM50634714(CHEMBL5527915)
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634711BDBM50634711(CHEMBL5557313)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
South Valley University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634708BDBM50634708(CHEMBL5523388)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) deacetylase activity using Ac-RHKK(Ac)-MCA as substrate incubated for 60 mins in presence of NAD by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed