Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50021705
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643750BDBM50643750(CHEMBL5575150)
Affinity DataIC50: 0.400nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643748BDBM50643748(CHEMBL5574671)
Affinity DataIC50: 0.700nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643763BDBM50643763(CHEMBL5594712)
Affinity DataIC50: 0.700nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643768BDBM50643768(CHEMBL5589825)
Affinity DataIC50: 1.90nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643749BDBM50643749(CHEMBL5566312)
Affinity DataIC50: 2.30nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643762BDBM50643762(CHEMBL5591151)
Affinity DataIC50: 2.40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643770BDBM50643770(CHEMBL5573122)
Affinity DataIC50: 2.5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643744BDBM50643744(CHEMBL4303573)
Affinity DataIC50: 2.70nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643780BDBM50643780(CHEMBL5590478)
Affinity DataIC50: 3.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643758BDBM50643758(CHEMBL5593424)
Affinity DataIC50: 5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643760BDBM50643760(CHEMBL5572905)
Affinity DataIC50: 5.30nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643759BDBM50643759(CHEMBL5572011)
Affinity DataIC50: 6nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643769BDBM50643769(CHEMBL5567438)
Affinity DataIC50: 6.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643784BDBM50643784(CHEMBL5565290)
Affinity DataIC50: 8.10nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643766BDBM50643766(CHEMBL5573131)
Affinity DataIC50: 8.5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643778BDBM50643778(CHEMBL5571595)
Affinity DataIC50: 9.40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643771BDBM50643771(Evetifator | DNL-343)
Affinity DataIC50: 9.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643783BDBM50643783(CHEMBL5569682)
Affinity DataIC50: 12nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643767BDBM50643767(CHEMBL5595443)
Affinity DataIC50: 12nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643772BDBM50643772(CHEMBL5564968)
Affinity DataIC50: 15nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643765BDBM50643765(CHEMBL5592433)
Affinity DataIC50: 19nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643752BDBM50643752(CHEMBL5565662)
Affinity DataIC50: 34nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643757BDBM50643757(CHEMBL5575064)
Affinity DataIC50: 40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643776BDBM50643776(CHEMBL5574460)
Affinity DataIC50: 52nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643782BDBM50643782(CHEMBL5570121)
Affinity DataIC50: 58nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643773BDBM50643773(CHEMBL5594694)
Affinity DataIC50: 61nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643781BDBM50643781(CHEMBL5575386)
Affinity DataIC50: 68nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643779BDBM50643779(CHEMBL5563612)
Affinity DataIC50: 103nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643751BDBM50643751(CHEMBL5570649)
Affinity DataIC50: 106nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643764BDBM50643764(CHEMBL5569542)
Affinity DataIC50: 111nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643761BDBM50643761(CHEMBL5570935)
Affinity DataIC50: 113nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643746BDBM50643746(CHEMBL5573833)
Affinity DataIC50: 141nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643755BDBM50643755(CHEMBL5595371)
Affinity DataIC50: 144nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643753BDBM50643753(CHEMBL5574838)
Affinity DataIC50: 159nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643785BDBM50643785(CHEMBL5566154)
Affinity DataIC50: 163nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643754BDBM50643754(CHEMBL5571155)
Affinity DataIC50: 183nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643786BDBM50643786(CHEMBL5570186)
Affinity DataIC50: 255nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643777BDBM50643777(CHEMBL5569689)
Affinity DataIC50: 377nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643774BDBM50643774(CHEMBL5570481)
Affinity DataIC50: 615nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643775BDBM50643775(CHEMBL5571502)
Affinity DataIC50: 1.00E+3nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643756BDBM50643756(CHEMBL5574907)
Affinity DataIC50: 1.30E+3nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643747BDBM50643747(CHEMBL5570348)
Affinity DataIC50: 1.00E+4nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643745BDBM50643745(CHEMBL5564460)
Affinity DataIC50: 1.00E+4nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed