Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50021300
TargetCREB-binding protein(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to CBP (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to p300 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCREB-binding protein(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CBP-BHC domain (unknown origin) assessed as measuring acetylation of biotinylated histone H4 peptide by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of p300-BHC domain (unknown origin) assessed as measuring acetylation of biotinylated histone H4 peptide by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  222nMAssay Description:Binding affinity to BRD4 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed