Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021303
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50155838((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of PREP (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human PREP proteolytic activity transfected in PREP knockout HEK293 cells using Suc-Gly-Pro-AMC as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
Affinity DataKd:  90nMAssay Description:Binding affinity to human wildype PREP assessed as binding constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50639285(CHEMBL5563880)
Affinity DataKd:  520nMAssay Description:Binding affinity to human wildype PREP assessed as binding constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50639285(CHEMBL5563880)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human PREP proteolytic activity transfected in PREP knockout HEK293 cells using Suc-Gly-Pro-AMC as substrate preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50639284(CHEMBL5567711)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant human PREP proteolytic activity transfected in PREP knockout HEK293 cells using Suc-Gly-Pro-AMC as substrate preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed