Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50019637
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614612(CHEMBL5280678)
Affinity DataIC50: 20nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50: 30nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621289(CHEMBL5410106)
Affinity DataIC50: 50nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614610(CHEMBL5267203)
Affinity DataIC50: 56nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621293(CHEMBL5439266)
Affinity DataIC50: 64nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621293(CHEMBL5439266)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614611(CHEMBL3400936)
Affinity DataIC50: 68nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621289(CHEMBL5410106)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621292(CHEMBL5405214)
Affinity DataIC50: 72nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50: 79nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614612(CHEMBL5280678)
Affinity DataIC50: 90nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621292(CHEMBL5405214)
Affinity DataIC50: 100nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621291(CHEMBL5434170)
Affinity DataIC50: 140nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614611(CHEMBL3400936)
Affinity DataIC50: 140nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621291(CHEMBL5434170)
Affinity DataIC50: 200nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621290(CHEMBL5403707)
Affinity DataIC50: 240nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614610(CHEMBL5267203)
Affinity DataIC50: 240nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621290(CHEMBL5403707)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed