Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50021777
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644788(CHEMBL5573487)
Affinity DataEC50:  15nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50154937(CHEMBL518800)
Affinity DataEC50:  16nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50378235(CHEMBL461557)
Affinity DataEC50:  17nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644794(CHEMBL5575551)
Affinity DataEC50:  18nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644790(CHEMBL5575056)
Affinity DataEC50:  21nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644795(CHEMBL5594035)
Affinity DataEC50:  21nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644787(CHEMBL5565816)
Affinity DataEC50:  28nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644796(CHEMBL5568619)
Affinity DataEC50:  35nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50479452(CHEMBL461556)
Affinity DataEC50:  36nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644797(CHEMBL5569096)
Affinity DataEC50:  36nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644801(CHEMBL5569293)
Affinity DataEC50:  41nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644789(CHEMBL5593913)
Affinity DataEC50:  44nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644798(CHEMBL5574391)
Affinity DataEC50:  46nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644793(CHEMBL5592449)
Affinity DataEC50:  57nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644791(CHEMBL5565299)
Affinity DataEC50:  60nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644786(CHEMBL5573271)
Affinity DataEC50:  78nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644792(CHEMBL5563303)
Affinity DataEC50:  182nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644799(CHEMBL5568703)
Affinity DataEC50:  246nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644800(CHEMBL5594597)
Affinity DataEC50:  603nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataEC50:  703nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed