Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50021726
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644089BDBM50644089(CHEMBL5574726)
Affinity DataKd:  0.00200nMAssay Description:Binding affinity to recombinant human CSF-1R assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644091BDBM50644091(CHEMBL5590377)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644099BDBM50644099(CHEMBL5572399)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644098BDBM50644098(CHEMBL5573389)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644094BDBM50644094(CHEMBL5570694)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644082BDBM50644082(CHEMBL5590280)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644083BDBM50644083(CHEMBL5575095)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587320BDBM50587320(CHEMBL5079522)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644086BDBM50644086(CHEMBL5566345)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644097BDBM50644097(CHEMBL5576024)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644093BDBM50644093(CHEMBL5583780)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644089BDBM50644089(CHEMBL5574726)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644090BDBM50644090(CHEMBL5569406)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644092BDBM50644092(CHEMBL5570142)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644095BDBM50644095(CHEMBL5573056)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644085BDBM50644085(CHEMBL5568712)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644084BDBM50644084(CHEMBL5595463)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644079BDBM50644079(CHEMBL5591166)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644103BDBM50644103(CHEMBL5567261)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644104BDBM50644104(CHEMBL5569967)
Affinity DataIC50: 8nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644087BDBM50644087(CHEMBL5573590)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644088BDBM50644088(CHEMBL5570015)
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644096BDBM50644096(CHEMBL5579732)
Affinity DataIC50: 12nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644074BDBM50644074(CHEMBL5593264)
Affinity DataIC50: 18nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 18nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644101BDBM50644101(CHEMBL5568944)
Affinity DataIC50: 20nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644100BDBM50644100(CHEMBL5571986)
Affinity DataIC50: 21nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644077BDBM50644077(CHEMBL5593484)
Affinity DataIC50: 69nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644080BDBM50644080(CHEMBL5571395)
Affinity DataIC50: 74nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644081BDBM50644081(CHEMBL5564414)
Affinity DataIC50: 75nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644102BDBM50644102(CHEMBL5563359)
Affinity DataIC50: 115nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644078BDBM50644078(CHEMBL5595497)
Affinity DataIC50: 118nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644073BDBM50644073(CHEMBL5574580)
Affinity DataIC50: 805nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644076BDBM50644076(CHEMBL5562550)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644075BDBM50644075(CHEMBL5570281)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644072BDBM50644072(CHEMBL5569918)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644071BDBM50644071(CHEMBL5574892)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed