Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50021337
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639675(CHEMBL5564604)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639671(CHEMBL5562964)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639676(CHEMBL5557812)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639677(CHEMBL5561163)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639673(CHEMBL5559694)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataKd:  8.70nMAssay Description:Binding affinity to human PTPN2 assessed as dissociation constant measured upto 300 secs by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639672(CHEMBL5564299)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639678(CHEMBL5560433)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639679(CHEMBL5567463)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639677(CHEMBL5561163)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM734322(US20250129032, Example 30)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639680(CHEMBL5561180)
Affinity DataIC50: 28nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639681(CHEMBL5561290)
Affinity DataIC50: 76nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639674(CHEMBL5561962)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed