Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50021736
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644331(CHEMBL5571220)
Affinity DataEC50:  0.0200nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644338(CHEMBL5565019)
Affinity DataEC50:  0.0300nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644341(CHEMBL5564020)
Affinity DataEC50:  0.0410nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  0.200nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644332(CHEMBL5571181)
Affinity DataEC50:  0.400nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644337(CHEMBL5567160)
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as increase in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644330(CHEMBL5563875)
Affinity DataEC50:  0.600nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644336(CHEMBL1579165)
Affinity DataEC50:  0.700nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595740(CHEMBL5202745)
Affinity DataEC50:  0.800nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644342(CHEMBL5565003)
Affinity DataEC50:  0.890nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644328(CHEMBL5594077)
Affinity DataEC50:  0.900nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644331(CHEMBL5571220)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644337(CHEMBL5567160)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644325(CHEMBL5564905)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644330(CHEMBL5563875)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  1.20nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  1.60nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644325(CHEMBL5564905)
Affinity DataEC50:  1.60nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644322(CHEMBL5572574)
Affinity DataIC50: 1.80nMAssay Description:Negative allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644325(CHEMBL5564905)
Affinity DataEC50:  2nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644332(CHEMBL5571181)
Affinity DataEC50:  2.20nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644328(CHEMBL5594077)
Affinity DataEC50:  2.5nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644328(CHEMBL5594077)
Affinity DataEC50:  2.80nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644340(CHEMBL5569996)
Affinity DataEC50:  3nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644333(CHEMBL5590998)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644323(CHEMBL5572226)
Affinity DataIC50: 4.20nMAssay Description:Negative allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644327(CHEMBL5583680)
Affinity DataEC50:  4.30nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644334(CHEMBL5573416)
Affinity DataEC50:  5.30nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644333(CHEMBL5590998)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644339(CHEMBL5571309)
Affinity DataEC50:  6.10nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644334(CHEMBL5573416)
Affinity DataEC50:  6.10nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644340(CHEMBL5569996)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as increase in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644327(CHEMBL5583680)
Affinity DataEC50:  15nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644335(CHEMBL5573090)
Affinity DataEC50:  23nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644327(CHEMBL5583680)
Affinity DataEC50:  58nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644324(CHEMBL5573743)
Affinity DataIC50: 125nMAssay Description:Negative allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644329(CHEMBL1393473)
Affinity DataEC50:  132nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644329(CHEMBL1393473)
Affinity DataEC50:  132nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644324(CHEMBL5573743)
Affinity DataIC50: 344nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644324(CHEMBL5573743)
Affinity DataIC50: 344nMAssay Description:Negative allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644345(CHEMBL5591700)
Affinity DataIC50: 400nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 716nMAssay Description:Negative allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644343(CHEMBL5570919)
Affinity DataIC50: 752nMAssay Description:Negative allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as decrease in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 924nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644343(CHEMBL5570919)
Affinity DataIC50: 1.04E+3nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644344(CHEMBL5565347)
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 1.49E+3nMAssay Description:Negative allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed