Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50021742
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50047019(CHEMBL269538 | 7-methoxy-1-methyl-9H-pyrido[3,4-b]...)
Affinity DataIC50: 21nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50: 57nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644371(CHEMBL5594692)
Affinity DataIC50: 209nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644371(CHEMBL5594692)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]-LSD from 5-HT2C receptor (unknown origin) expressed in HEK293T cell membrane assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644372(CHEMBL5567330)
Affinity DataIC50: 561nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644372(CHEMBL5567330)
Affinity DataKi:  962nMAssay Description:Displacement of [3H]-LSD from 5-HT2C receptor (unknown origin) expressed in HEK293T cell membrane assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644371(CHEMBL5594692)
Affinity DataKi:  1.61E+3nMAssay Description:Displacement of [3H]-LSD from 5-HT2A receptor (unknown origin) expressed in HEK293T cell membrane assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644370(CHEMBL5569583)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644369(CHEMBL5575454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644374(CHEMBL5573704)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50644373(CHEMBL5574812)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed