Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50021744
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM700108(US20240335569, Compound 3BP-2929 | US20240382629, ...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of FAP (unknown origin) using Z-Gly-Pro-7-amino-4-methylcoumarine as fluorogenic substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of C-terminal His-tagged recombinant human FAP extracellular domain (27 to 760 residues) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of FAP (unknown origin) using Z-Gly-Pro-7-amino-4-methylcoumarine as fluorogenic substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644385(CHEMBL5572035)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FAP (unknown origin) using Z-Gly-Pro-7-amino-4-methylcoumarine as fluorogenic substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FAP (unknown origin) using Z-Gly-Pro-7-amino-4-methylcoumarine as fluorogenic substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of FAP (unknown origin) using Z-Gly-Pro-7-amino-4-methylcoumarine as fluorogenic substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of DPP9 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644385(CHEMBL5572035)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PREP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of DPP8 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM700108(US20240335569, Compound 3BP-2929 | US20240382629, ...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PREP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin) using Lys-Ala-pNA as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin) using Lys-Ala-pNA as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin) using Lys-Ala-pNA as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin) using Lys-Ala-pNA as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin) using Lys-Ala-pNA as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PREP (unknown origin) using N-succinyl-Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PREP (unknown origin) using N-succinyl-Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PREP (unknown origin) using N-succinyl-Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PREP (unknown origin) using N-succinyl-Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PREP (unknown origin) using N-succinyl-Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644380(CHEMBL5562853)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644382(CHEMBL5569691)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644381(CHEMBL5590792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644384(CHEMBL5566777)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50644383(CHEMBL5566659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8 (unknown origin) using Ala-Pro-paranitroanilide as chromogenic substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed