Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50020811
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50: 5nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50614629(BAY-293)
Affinity DataIC50: 21nMAssay Description:Inhibition of human SOS1 catalytic domain (560 to 1049 residues)/KRAS G12C mutant (1 to 169 residues) expressed in Escherichia coli incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50633724(CHEMBL5431572)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of his tagged SOS1/GST-tagged KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50633723(CHEMBL5413389)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of his tagged SOS1/GST-tagged KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50633725(CHEMBL5425623)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of his tagged SOS1/GST-tagged KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandPNGBDBM50633722(CHEMBL5429741)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of his tagged SOS1/GST-tagged KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed