Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50021085
Affinity DataKd: 1.10E+3nMAssay Description:Binding affinity to C-terminally avi-tagged human IL-1 beta assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at human IL-1 beta assessed as inhibition of interaction of IL-1beta/IL-1R1 expressed in HEK293-Blue cells by measuring reduction...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at human IL-1 beta assessed as inhibition of interaction of IL-1 beta/IL-1R1 expressed in NHDF cells by measuring reduction in IL...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of (S)-3-(5-chloro-2-hydroxyphenyl)-3-hydroxy-6-(trifluoromethyl)indolin-2-one from biotinylated His6-tagged human IL-1 beta (117 to 269...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+4nMAssay Description:Displacement of (S)-3-(5-chloro-2-hydroxyphenyl)-3-hydroxy-6-(trifluoromethyl)indolin-2-one from biotinylated His6-tagged human IL-1 beta (117 to 269...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Displacement of (S)-3-(5-chloro-2-hydroxyphenyl)-3-hydroxy-6-(trifluoromethyl)indolin-2-one from biotinylated His6-tagged human IL-1 beta (117 to 269...More data for this Ligand-Target Pair
Affinity DataIC50: 7.84E+4nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+4nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Affinity DataKi: 2.27E+5nMAssay Description:Displacement of (S)-3-(5-chloro-2-hydroxyphenyl)-3-hydroxy-6-(trifluoromethyl)indolin-2-one from biotinylated His6-tagged human IL-1 beta (117 to 269...More data for this Ligand-Target Pair
Affinity DataKd: 2.87E+5nMAssay Description:Binding affinity to human IL-1 beta expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by 2D NMR titration based analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of (S)-3-(5-chloro-2-hydroxyphenyl)-3-hydroxy-6-(trifluoromethyl)indolin-2-one from biotinylated His6-tagged human IL-1 beta (117 to 269...More data for this Ligand-Target Pair
