Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50021090
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636707(CHEMBL5559200)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636713(CHEMBL5523492)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636711(CHEMBL5557640)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636704(CHEMBL5542161)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636710(CHEMBL5518060)
Affinity DataEC50:  330nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636708(CHEMBL5568270)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636705(CHEMBL5555642)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636712(CHEMBL5542946)
Affinity DataEC50:  490nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50320072(1-Benzyl-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine...)
Affinity DataEC50:  850nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636706(CHEMBL5567837)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50629426(CHEMBL5400489)
Affinity DataEC50:  1.83E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636703(CHEMBL5542316)
Affinity DataEC50:  2.81E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636702(CHEMBL5558920)
Affinity DataEC50:  2.92E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50636709(CHEMBL5567154)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 7(Human)TBA
LigandPNGBDBM50240849(1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-ami...)
Affinity DataEC50:  8.29E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50636704(CHEMBL5542161)
Affinity DataEC50:  1.83E+4nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50636711(CHEMBL5557640)
Affinity DataEC50:  2.58E+4nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50636707(CHEMBL5559200)
Affinity DataEC50:  3.18E+4nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50636712(CHEMBL5542946)
Affinity DataEC50:  5.03E+4nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetToll-like receptor 8(Human)TBA
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  1.25E+5nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed