Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50022476
LigandPNGBDBM50652763(CHEMBL5646411 | US20250268877, Example 84)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50652765(CHEMBL5647518)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652761(CHEMBL5639259 | US20250268877, Example 76)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652755(CHEMBL5647042 | US20250268877, Example 8)
Affinity DataIC50: 0.284nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652762(CHEMBL5646604)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652759(CHEMBL5646502)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652754(CHEMBL5641831 | US20250268877, Comparator 1B)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652756(CHEMBL5647179)
Affinity DataIC50: 0.752nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652753(CHEMBL5647375 | US20250268877, Comparator 1A)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652749(CHEMBL5639891)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652750(CHEMBL5646687)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652757(CHEMBL5646690)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652764(CHEMBL5639415 | US20250268877, Example 83)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50652752(CHEMBL5646716)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652754(CHEMBL5641831 | US20250268877, Comparator 1B)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652751(CHEMBL5646886)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652758(CHEMBL5646877)
Affinity DataIC50: 16nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652760(CHEMBL5639909 | US20250268877, Example 71)
Affinity DataIC50: 22nMAssay Description:Inhibition of IRAK4 (unknown origin) incubated for 1 hr in presence of ATP by Mesoscale assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652763(CHEMBL5646411 | US20250268877, Example 84)
Affinity DataIC50: 31nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50652755(CHEMBL5647042 | US20250268877, Example 8)
Affinity DataIC50: 52nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652753(CHEMBL5647375 | US20250268877, Comparator 1A)
Affinity DataIC50: 81nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652765(CHEMBL5647518)
Affinity DataIC50: 165nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652761(CHEMBL5639259 | US20250268877, Example 76)
Affinity DataIC50: 743nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652762(CHEMBL5646604)
Affinity DataIC50: 834nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652764(CHEMBL5639415 | US20250268877, Example 83)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-1beta production preincubated with compound for 1 hr followed by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)