Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50020947
TargetPlasminogen(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635294(CHEMBL5557468)
Affinity DataKi:  0.810nMAssay Description:Binding affinity to plasmin (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50125333(CHEMBL3623612)
Affinity DataKi:  4nMAssay Description:Binding affinity to wild type FKBP51 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-3(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579637(CHEMBL4878958)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PIM3 (unknown origin) by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50125330(CHEMBL3623630)
Affinity DataKi:  6nMAssay Description:Binding affinity to wild type FKBP51 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635293(CHEMBL5542668)
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579637(CHEMBL4878958)
Affinity DataIC50: 8nMAssay Description:Inhibition of PIM2 (unknown origin) by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635291(CHEMBL5559024)
Affinity DataIC50: 10nMAssay Description:Inhibition of CGRP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579637(CHEMBL4878958)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PIM1 by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 36nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635296(CHEMBL5512498)
Affinity DataKd:  40nMAssay Description:Binding affinity to recombinant human wild type STING expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by Surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-citrate synthase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataIC50: 44nMAssay Description:Inhibition of ATP citrate lyase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataKd:  70nMAssay Description:Binding affinity to recombinant human wild type STING expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by Surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-citrate synthase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50624085(CHEMBL5439664)
Affinity DataIC50: 70nMAssay Description:Inhibition of ATP citrate lyase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579637(CHEMBL4878958)
Affinity DataIC50: 75nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50575646(CHEMBL4876664)
Affinity DataKd:  83nMAssay Description:Binding affinity to FKBP51 (unknown origin) assessed as dissociation constant by fluorescence polarization based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-citrate synthase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataKd:  128nMAssay Description:Binding affinity to ATP citrate lyase (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataKd:  186nMAssay Description:Binding affinity to AKT1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1B(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50575646(CHEMBL4876664)
Affinity DataKd:  203nMAssay Description:Binding affinity to human FKBP12.6 assessed as dissociation constant incubated for 30 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 237nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) expressed in baculovirus expression system Sf9 cells incubated for 30 mins in presence of ATP by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50575646(CHEMBL4876664)
Affinity DataKd:  263nMAssay Description:Binding affinity to FKBP12 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscleblind-like protein 1(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635292(CHEMBL3102959)
Affinity DataKd:  300nMAssay Description:Binding affinity to MBNL1 (unknown origin) (1 to 272 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-citrate synthase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50624085(CHEMBL5439664)
Affinity DataKd:  376nMAssay Description:Binding affinity to ATP citrate lyase (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579641(CHEMBL4874628)
Affinity DataIC50: 604nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProthrombin(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635294(CHEMBL5557468)
Affinity DataKi:  667nMAssay Description:Binding affinity to thrombin (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635296(CHEMBL5512498)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human wild type STING expressed in human THP-1 cells assessed increase in IRF3 phosphorylation incubated for 6 hrs by Western blo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635296(CHEMBL5512498)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human STING AQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635296(CHEMBL5512498)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human STING HAQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635296(CHEMBL5512498)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at human STING REF variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50575646(CHEMBL4876664)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to FKBP52 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50579641(CHEMBL4874628)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIM1 by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  3.85E+4nMAssay Description:Agonist activity at human STING REF variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50125333(CHEMBL3623612)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to FKBP52 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50125330(CHEMBL3623630)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to FKBP52 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.35E+4nMAssay Description:Agonist activity at human STING HAQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.50E+4nMAssay Description:Agonist activity at human wild type STING expressed in human THP-1 cells assessed increase in IRF3 phosphorylation incubated for 6 hrs by Western blo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.59E+4nMAssay Description:Agonist activity at human STING AQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed