Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50021942
LigandPNGBDBM50529751(CHEMBL4472979 | US10913710, Compound 16)
Affinity DataKd:  0.110nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50646344(CHEMBL5594211)
Affinity DataKd:  0.300nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646343(CHEMBL5595916)
Affinity DataKd:  1.30nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646349(CHEMBL5595364)
Affinity DataKd:  1.5nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646348(CHEMBL5592316)
Affinity DataKd:  1.60nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50249989(CHEMBL1387422)
Affinity DataKd:  3.80nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646335(CHEMBL5595347)
Affinity DataKd:  4nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646345(CHEMBL5591954)
Affinity DataKd:  4.5nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646342(CHEMBL5583878)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646346(CHEMBL5592494)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646337(CHEMBL5592414)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646341(CHEMBL5591087)
Affinity DataKd:  7.20nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646334(CHEMBL5590495)
Affinity DataKd:  9nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646339(CHEMBL5591013)
Affinity DataKd:  16nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646336(CHEMBL5590801)
Affinity DataKd:  39nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50019865(CHEMBL3286929)
Affinity DataKd:  39nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646340(CHEMBL5593139)
Affinity DataKd:  100nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646351(CHEMBL5592067)
Affinity DataKd:  127nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from PDEdelta (unknown origin) assessed as dissociation constant incubated for 10 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646338(CHEMBL5590787)
Affinity DataKd:  287nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646352(CHEMBL5593443)
Affinity DataKd:  436nMAssay Description:Binding affinity to N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) assessed as dissociation constant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50646337(CHEMBL5592414)
Affinity DataKd:  630nMAssay Description:Displacement of fluorescein-labeled Ras homologue enriched in brain peptide probe from N-terminal His6 tagged human recombinant PDE6D extracted from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646347(CHEMBL5594126)
Affinity DataKd:  763nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGTPase KRas(Human)TBA
LigandPNGBDBM50646348(CHEMBL5592316)
Affinity DataEC50:  1.30E+3nMAssay Description:Induction of Rluc8-tagged and GFP2-tagged K-Ras G12V mutant (unknown origin) disruption extracted from HEK293-EBNA cells assessed as intracellular K-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGTPase KRas(Human)TBA
LigandPNGBDBM50249989(CHEMBL1387422)
Affinity DataEC50:  1.80E+3nMAssay Description:Induction of Rluc8-tagged and GFP2-tagged K-Ras G12V mutant (unknown origin) disruption extracted from HEK293-EBNA cells assessed as intracellular K-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGTPase HRas(Human)TBA
LigandPNGBDBM50646348(CHEMBL5592316)
Affinity DataEC50:  2.60E+3nMAssay Description:Induction of Rluc8-tagged and GFP2-tagged H-Ras G12V mutant (unknown origin) disruption extracted from HEK293-EBNA cells assessed as intracellular H-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGTPase KRas(Human)TBA
LigandPNGBDBM50646337(CHEMBL5592414)
Affinity DataEC50:  3.00E+3nMAssay Description:Induction of Rluc8-tagged and GFP2-tagged K-Ras G12V mutant (unknown origin) disruption extracted from HEK293-EBNA cells assessed as intracellular K-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGTPase HRas(Human)TBA
LigandPNGBDBM50249989(CHEMBL1387422)
Affinity DataEC50:  5.00E+3nMAssay Description:Induction of Rluc8-tagged and GFP2-tagged H-Ras G12V mutant (unknown origin) disruption extracted from HEK293-EBNA cells assessed as intracellular H-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646350(CHEMBL5593218)
Affinity DataKd:  7.17E+3nMAssay Description:Displacement of fluorescein-labeled Ras homologue enriched in brain peptide probe from N-terminal His6 tagged human recombinant PDE6D extracted from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed