Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50021857
TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of ALK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of ALK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645526(CHEMBL5593625)
Affinity DataIC50: 15nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645534(CHEMBL5589799)
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645531(CHEMBL5590063)
Affinity DataIC50: 18nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 18nMAssay Description:Inhibition of ACTR2B (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645532(CHEMBL5592344)
Affinity DataIC50: 20nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645502(CHEMBL5595734)
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645502(CHEMBL5595734)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human ALK5 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645510(CHEMBL5591352)
Affinity DataIC50: 33nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645524(CHEMBL5583950)
Affinity DataIC50: 35nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645523(CHEMBL5589967)
Affinity DataIC50: 36nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645509(CHEMBL5594759)
Affinity DataIC50: 37nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645521(CHEMBL5592764)
Affinity DataIC50: 38nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645518(CHEMBL5591092)
Affinity DataIC50: 40nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645504(CHEMBL5592048)
Affinity DataIC50: 48nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 56nMAssay Description:Inhibition of ALK3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645514(CHEMBL5592076)
Affinity DataIC50: 58nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645519(CHEMBL5583978)
Affinity DataIC50: 63nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645520(CHEMBL5590786)
Affinity DataIC50: 64nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 69nMAssay Description:Inhibition of ACTR2B (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645506(CHEMBL5583785)
Affinity DataIC50: 70nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 74nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 77nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645511(CHEMBL5584022)
Affinity DataIC50: 79nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 82nMAssay Description:Inhibition of ALK6 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645512(CHEMBL5583778)
Affinity DataIC50: 83nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645535(CHEMBL5584140)
Affinity DataIC50: 93nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645533(CHEMBL5593082)
Affinity DataIC50: 93nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645515(CHEMBL5595883)
Affinity DataIC50: 102nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645505(CHEMBL5589852)
Affinity DataIC50: 105nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645503(CHEMBL5589928)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human ALK5 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645525(CHEMBL5590150)
Affinity DataIC50: 150nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645522(CHEMBL5595316)
Affinity DataIC50: 162nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 183nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645516(CHEMBL5593207)
Affinity DataIC50: 229nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 232nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645508(CHEMBL5590237)
Affinity DataIC50: 294nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645507(CHEMBL5594194)
Affinity DataIC50: 310nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645517(CHEMBL5595230)
Affinity DataIC50: 363nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645513(CHEMBL5583783)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of ALK3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645538(CHEMBL5595138)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ALK6 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645530(CHEMBL5593640)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645529(CHEMBL5592752)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of ALK5 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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