Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50021352
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639776BDBM50639776(CHEMBL5559267)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639777BDBM50639777(CHEMBL5561389)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639790BDBM50639790(CHEMBL5567099)
Affinity DataIC50: 13nMAssay Description:Inhibition of human c-MetMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639777BDBM50639777(CHEMBL5561389)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541920BDBM50541920(Lirametostat | Cpi-1205)
Affinity DataIC50: 32nMAssay Description:Inhibition of EZH2 in human HeLa cells assessed as reduction in H3K27-me3 level incubated for 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551861BDBM50551861(CHEMBL4798849)
Affinity DataIC50: 50nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625503BDBM50625503(CHEMBL5414728)
Affinity DataIC50: 63nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639788BDBM50639788(CHEMBL5565160)
Affinity DataIC50: 70nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 173537BDBM173537((E)-N'-(4-hydroxybenzylidene)-1H-indole-2-carb...)
Affinity DataIC50: 70nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639775BDBM50639775(CHEMBL5563020)
Affinity DataIC50: 75nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79601BDBM79601(4-[4-[[[4-chloro-3-(trifluoromethyl)anilino]-oxome...)
Affinity DataIC50: 90nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmin(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450704BDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataKi:  440nMAssay Description:Binding affinity to Grp94 (unknown origin) assessed as inhibition constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639774BDBM50639774(CHEMBL5561899)
Affinity DataIC50: 451nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551914BDBM50551914(CHEMBL4742730)
Affinity DataIC50: 540nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461016BDBM50461016(CHEMBL4226393)
Affinity DataIC50: 720nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625503BDBM50625503(CHEMBL5414728)
Affinity DataIC50: 725nMAssay Description:Inhibition of human ALKL1196M mutant by discoverX kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639791BDBM50639791(CHEMBL5532090)
Affinity DataIC50: 790nMAssay Description:Inhibition of c-Met (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639783BDBM50639783(CHEMBL5567316)
Affinity DataIC50: 970nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639787BDBM50639787(CHEMBL5563102)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639789BDBM50639789(CHEMBL5566160)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639792BDBM50639792(CHEMBL5563390)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of B-Raf (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350996BDBM50350996(CHEMBL1818877)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407801BDBM50407801(CHEMBL5284058)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 as a substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610759BDBM50610759(CHEMBL5272233)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of DNA topoisomerase I (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610760BDBM50610760(CHEMBL5279607)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of DNA topoisomerase I (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639785BDBM50639785(CHEMBL5557572)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human EZH2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610760BDBM50610760(CHEMBL5279607)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of KSP/Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639784BDBM50639784(CHEMBL5562976)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human EZH2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486734BDBM50486734(CHEMBL5289303)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610759BDBM50610759(CHEMBL5272233)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of KSP/Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486735BDBM50486735(CHEMBL5274698)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639773BDBM50639773(CHEMBL5549803)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of KSP/Eg5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosinase(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639782BDBM50639782(CHEMBL5559595)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639786BDBM50639786(CHEMBL5560502)
Affinity DataIC50: 2.49E+4nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosinase(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639781BDBM50639781(CHEMBL5566067)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639773BDBM50639773(CHEMBL5549803)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of DNA topoisomerase I (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639772BDBM50639772(CHEMBL5564484)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of DNA topoisomerase I (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639772BDBM50639772(CHEMBL5564484)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of KSP/Eg5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639780BDBM50639780(CHEMBL5562705)
Affinity DataIC50: 9.42E+4nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407801BDBM50407801(CHEMBL5284058)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of MAO-B (unknown origin) by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosinase(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 173537BDBM173537((E)-N'-(4-hydroxybenzylidene)-1H-indole-2-carb...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639778BDBM50639778(CHEMBL5555544)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639779BDBM50639779(CHEMBL5558497)
Affinity DataIC50: 3.45E+5nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610772BDBM50610772(CHEMBL5287554)
Affinity DataIC50: 3.72E+5nMAssay Description:Inhibition of mushroom TyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed