Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50021105
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636905(CHEMBL5563072)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636904(CHEMBL5558071)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636906(CHEMBL5557899)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636908(CHEMBL5556819)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636919(CHEMBL5531948)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636918(CHEMBL5562417)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM50636904(CHEMBL5558071)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM50636912(CHEMBL5562301)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636907(CHEMBL5532572)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636916(CHEMBL5556681)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM683053(US12023331, Example 1 | US20240307386, Compound Ex...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636913(CHEMBL5557169)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636914(CHEMBL5560998)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM683053(US12023331, Example 1 | US20240307386, Compound Ex...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636915(CHEMBL5568594)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636921(CHEMBL5563721)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636907(CHEMBL5532572)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM50636908(CHEMBL5556819)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636920(CHEMBL5558436)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636904(CHEMBL5558071)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636917(CHEMBL5517931)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636909(CHEMBL5568395)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636905(CHEMBL5563072)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636911(CHEMBL5518013)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636906(CHEMBL5557899)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636912(CHEMBL5562301)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636908(CHEMBL5556819)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636904(CHEMBL5558071)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM683053(US12023331, Example 1 | US20240307386, Compound Ex...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636913(CHEMBL5557169)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636911(CHEMBL5518013)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM50636914(CHEMBL5560998)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636908(CHEMBL5556819)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636910(CHEMBL5542837)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM683053(US12023331, Example 1 | US20240307386, Compound Ex...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636912(CHEMBL5562301)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636914(CHEMBL5560998)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)TBA
LigandPNGBDBM50636905(CHEMBL5563072)
Affinity DataKi:  232nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMu-type opioid receptor(Human)TBA
LigandPNGBDBM50636914(CHEMBL5560998)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 120 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636905(CHEMBL5563072)
Affinity DataKi:  508nMAssay Description:Displacement of [3H]-imipramine from human 5-HT transporter expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636904(CHEMBL5558071)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]-imipramine from human 5-HT transporter expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM683053(US12023331, Example 1 | US20240307386, Compound Ex...)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-imipramine from human 5-HT transporter expressed in CHO cell membrane assessed as inhibition constant incubated for 60 mins by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)TBA
LigandPNGBDBM50636905(CHEMBL5563072)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50636912(CHEMBL5562301)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed