Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50021218
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of p300 (unknown origin) using histone H3 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate and [3H]Ac-CoA ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 6nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 7nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 11nMAssay Description:Inhibition of CBP (unknown origin) using histone H3 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate and [3H]Ac-CoA add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50638388(CHEMBL5560381)
Affinity DataIC50: 20nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50638390(CHEMBL5558461)
Affinity DataIC50: 21nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638388(CHEMBL5560381)
Affinity DataIC50: 22nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 26nMAssay Description:Binding affinity to CBP (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638390(CHEMBL5558461)
Affinity DataIC50: 30nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50638389(CHEMBL5556365)
Affinity DataIC50: 36nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638387(CHEMBL5565647)
Affinity DataIC50: 46nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638389(CHEMBL5556365)
Affinity DataIC50: 51nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50638387(CHEMBL5565647)
Affinity DataIC50: 68nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50638391(CHEMBL5532417)
Affinity DataIC50: 73nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638391(CHEMBL5532417)
Affinity DataIC50: 77nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50638390(CHEMBL5558461)
Affinity DataIC50: 180nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50638388(CHEMBL5560381)
Affinity DataIC50: 470nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50638387(CHEMBL5565647)
Affinity DataIC50: 790nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50638391(CHEMBL5532417)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50638389(CHEMBL5556365)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed