Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50021229
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638490(CHEMBL5288063)
Affinity DataIC50: 20nMAssay Description:Inhibition of ASM (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638486(CHEMBL5559723)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638491(CHEMBL5556497)
Affinity DataIC50: 440nMAssay Description:Inhibition of ASM (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638482(CHEMBL5542512)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632364(CHEMBL5413803)
Affinity DataIC50: 510nMAssay Description:Inhibition of ASM (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638481(CHEMBL5566028)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638488(CHEMBL5559942)
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638484(CHEMBL5542640)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638483(CHEMBL5542655)
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638489(CHEMBL5568173)
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638492(CHEMBL5556653)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of ASM (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638487(CHEMBL5565575)
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638485(CHEMBL5565678)
Affinity DataIC50: 6.54E+3nMAssay Description:Inhibition of human recombinant ASM (His62 to Pro628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50214969(Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of bovine brain acidic sphingomyelinase using NBD-sphingomyelin as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed