Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50020964
TargetMuscarinic acetylcholine receptor M4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50608203(CHEMBL5287400)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor in presence of EC20 concentration of acetylcholine by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50635592(Cvl-231 | Emraclidine | Pf-06852231 | CVL-231 | PF...)
Affinity DataEC50:  4.80E+3nMAssay Description:Positive allosteric modulation of human M2 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50635592(Cvl-231 | Emraclidine | Pf-06852231 | CVL-231 | PF...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M1 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50635592(Cvl-231 | Emraclidine | Pf-06852231 | CVL-231 | PF...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M5 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50635592(Cvl-231 | Emraclidine | Pf-06852231 | CVL-231 | PF...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human M3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed