Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50021575
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642109(CHEMBL5574998)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642105(CHEMBL5566255)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642110(CHEMBL5573352)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642101(CHEMBL5589635)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642104(CHEMBL5569972)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642106(CHEMBL5571383)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642107(CHEMBL5591438)
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642104(CHEMBL5569972)
Affinity DataKd:  3.28E+4nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642101(CHEMBL5589635)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642107(CHEMBL5591438)
Affinity DataKd:  3.78E+4nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642106(CHEMBL5571383)
Affinity DataKd:  4.98E+4nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642108(CHEMBL5575889)
Affinity DataIC50: 6.26E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642102(CHEMBL5565663)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642103(CHEMBL5570014)
Affinity DataIC50: 6.35E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642111(CHEMBL5594098)
Affinity DataIC50: 6.69E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using MCA-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642104(CHEMBL5569972)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642109(CHEMBL5574998)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642108(CHEMBL5575889)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642107(CHEMBL5591438)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642106(CHEMBL5571383)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642103(CHEMBL5570014)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642102(CHEMBL5565663)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642101(CHEMBL5589635)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642110(CHEMBL5573352)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642105(CHEMBL5566255)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642104(CHEMBL5569972)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642112(CHEMBL5542957)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642109(CHEMBL5574998)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642108(CHEMBL5575889)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642107(CHEMBL5591438)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642106(CHEMBL5571383)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642110(CHEMBL5573352)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642103(CHEMBL5570014)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642102(CHEMBL5565663)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642101(CHEMBL5589635)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642105(CHEMBL5566255)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642112(CHEMBL5542957)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642112(CHEMBL5542957)
Affinity DataKd:  1.85E+5nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642108(CHEMBL5575889)
Affinity DataKd:  3.24E+5nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataKd:  3.68E+5nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed