Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50020970
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM652566(US20240059691, Example 1305 | (S*)-N5-((4-methyl-6...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FXIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataKi:  11nMAssay Description:Binding affinity to FXIIa (unknown origin) assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM476458((2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- [(4R,5S)-4-m...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human FXIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 29nMAssay Description:Inhibition of human FXIIa using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 35nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 37nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635637(CHEMBL5557890)
Affinity DataIC50: 39nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635636(CHEMBL5559399)
Affinity DataIC50: 40nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataKi:  44nMAssay Description:Binding affinity to FXIIa (unknown origin) assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635631(CHEMBL5556555)
Affinity DataIC50: 48nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635638(CHEMBL5523359)
Affinity DataIC50: 50nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635635(CHEMBL5558878)
Affinity DataIC50: 51nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635639(CHEMBL5517694)
Affinity DataIC50: 56nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635630(CHEMBL5523499)
Affinity DataIC50: 72nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635632(CHEMBL5549891)
Affinity DataIC50: 79nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635633(CHEMBL5558422)
Affinity DataIC50: 81nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635640(CHEMBL5558424)
Affinity DataIC50: 86nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635641(CHEMBL5542842)
Affinity DataIC50: 95nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635643(CHEMBL5542138)
Affinity DataIC50: 100nMAssay Description:Inhibition of human FXIIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 109nMAssay Description:Inhibition of human FXIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 163nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635627(CHEMBL5550076)
Affinity DataIC50: 180nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635629(CHEMBL5557937)
Affinity DataIC50: 190nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635628(CHEMBL5517825)
Affinity DataIC50: 195nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor XII(Human)TBA
LigandPNGBDBM50635626(CHEMBL5558338)
Affinity DataIC50: 202nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 360nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlasminogen(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor X(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FXa (unknown origin) using Z-D-Arg-Gly-Arg-pNA.2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlasminogen(Human)TBA
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor X(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FXa (unknown origin) using Z-D-Arg-Gly-Arg-pNA.2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-lle-Glu(gamma-OR)-Gly-Arg-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50548594(CHEMBL4776259)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-lle-Glu(gamma-OR)-Gly-Arg-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50548603(CHEMBL4761275)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50635637(CHEMBL5557890)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)TBA
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-lle-Glu(gamma-OR)-Gly-Arg-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)TBA
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)TBA
LigandPNGBDBM50635637(CHEMBL5557890)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlasminogen(Human)TBA
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlasminogen(Human)TBA
LigandPNGBDBM50635637(CHEMBL5557890)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlasminogen(Human)TBA
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635642(CHEMBL5517985)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635637(CHEMBL5557890)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Jump to: