Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50021878
LigandPNGBDBM50645726(CHEMBL361568)
Affinity DataIC50: 560nMAssay Description:Inhibition of human TRPV3 expressed in CHO cells assessed as reduction in 2-APB induced channel current at -80 mV by whole-cell patch clamp electroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50645726(CHEMBL361568)
Affinity DataIC50: 800nMAssay Description:Inhibition of human TRPV3 expressed in CHO cells assessed as reduction in 2-APB induced channel current at +80 mV by whole-cell patch clamp electroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50645726(CHEMBL361568)
Affinity DataIC50: 850nMAssay Description:Inhibition of TRPV3 in human HaCaT cells assessed as reduction in carvacrol-induced calcium influx measured for 60 mins by Fluo-4-AM dye based fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of mouse TRPV3 expressed in HEK293 cells assessed as reduction in 2-APB evoked current at -60 mV holding potential by whole-cell patch cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50625753(CHEMBL5425072)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human TRPV3 expressed in HEK293 cells assessed as reduction in 2-APB induced channel current at voltage ramp from -100 to +100 mV by wh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details