Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50020982
Affinity DataIC50: 1nMAssay Description:Inhibition of TMPRSS2 (unknown origin) using Boc-Gln-Ala-Arg-AMC as peptide substrate pre-incubated with compound for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant SARS-CoV-2 PLpro expressed in Escherichia coli BL21 (DE3) using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 expressed in Escherichia coli BL21(DE3) using ISG-AMC substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 expressed in Escherichia coli BL21(DE3) using ISG-AMC substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 expressed in Escherichia coli BL21(DE3) using ISG-AMC substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 expressed in Escherichia coli BL21(DE3) using ISG-AMC substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main protease by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 453nMAssay Description:Inhibition of SARS-CoV-2 main protease by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of furin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of SARS-CoV-2 main protease by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) using Boc-Gln-Ala-Arg-AMC as peptide substrate pre-incubated with compound for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of N-terminal His-tagged SARS-CoV-2 PLpro using Z-RLRGG-AMC as substrate pre-incubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of N-terminal His-tagged SARS-CoV-2 PLpro using Z-RLRGG-AMC as substrate pre-incubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human recombinant TMPRSS2 using Boc-Gln-Ala-Arg-AMC as peptide substrate pre-incubated with compound for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataKd: 1.24E+4nMAssay Description:Binding affinity to SARS-CoV-2 Main protease assessed as inhibition constant by Surface Plasmon ResonanceMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main protease by FRET analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.32E+4nMAssay Description:Binding affinity to SARS CoV-2 PLpro using Dabcyl-KTSAVLQ-SGFRKME-Edans as fluorogenic substrate incubated for 30 mins assessed as inhibition constan...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Affinity DataKd: 3.89E+5nMAssay Description:Binding affinity to recombinant hexa-His tagged SARS-COV-2 main protease expressed in Escherichia coli incubated for 1 hr by SDS-PAGE gel electrophor...More data for this Ligand-Target Pair
