Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50022196
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649314BDBM50649314(CHEMBL5618852)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649315BDBM50649315(CHEMBL5618796)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649316BDBM50649316(CHEMBL5619499)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649317BDBM50649317(CHEMBL5618233)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649318BDBM50649318(CHEMBL5619124)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649310BDBM50649310(CHEMBL5619733)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649313BDBM50649313(CHEMBL5619006)
Affinity DataIC50: 28nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649312BDBM50649312(CHEMBL5619926)
Affinity DataIC50: 33nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649311BDBM50649311(CHEMBL5619218)
Affinity DataIC50: 38nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649315BDBM50649315(CHEMBL5618796)
Affinity DataIC50: 64nMAssay Description:Inhibition of PDE4B (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649315BDBM50649315(CHEMBL5618796)
Affinity DataIC50: 66nMAssay Description:Inhibition of PDE4D (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248919BDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50: 74nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649320BDBM50649320(CHEMBL5619676)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human PDE4B catalytic domain extracted from baculovirus infected Sf9 cells using 5'-nucleotidase as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639239BDBM50639239(Rolipram | (r,s)-rolipram | NSC-760125 | SB-95952 ...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639239BDBM50639239(Rolipram | (r,s)-rolipram | NSC-760125 | SB-95952 ...)
Affinity DataIC50: 190nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639239BDBM50639239(Rolipram | (r,s)-rolipram | NSC-760125 | SB-95952 ...)
Affinity DataIC50: 240nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649308BDBM50649308(CHEMBL5618590)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649319BDBM50649319(CHEMBL5620310)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant PDE4D using radioactively labelled cAMP and cAMP as substrate incubated for 1 hrs by luminescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32024BDBM32024(DIPYRIDAMOLE)
Affinity DataIC50: 600nMAssay Description:Inhibition of PDE7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649307BDBM50649307(CHEMBL5619117)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649309BDBM50649309(CHEMBL5619137)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE4D7 (unknown origin) using FAM-cyclic-3'5'-AMP as substrate incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32024BDBM32024(DIPYRIDAMOLE)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed