Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50003248
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026275(2-(4-{[(2,4-Diamino-quinazolin-6-yl)-methyl-amino]...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026277(2-(4-{[(2,4-Diamino-quinazolin-6-yl)-formyl-amino]...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026273(2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-amino]-b...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026276(2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-formyl-a...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of rat liver DHFR assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026274(2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-methyl-a...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of rat liver DHFR assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026272(2-{4-[(2,4-Diamino-quinazolin-6-ylamino)-methyl]-b...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed