Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50023061
Affinity DataIC50: 0.170nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibition of PARP1 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PARP1 in PARP2 knockout human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by sel...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Binding affinity to PARP1 (unknown origin) assessed as DNA trapping activity incubated for 1 hr by Envision 2105 plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PARP1 in PARP2 knockout human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by sel...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 4.10nMAssay Description:Inhibition of PARP1 in wild type human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by PARylati...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of PARP1 in wild type human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by PARylati...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of PARP2 (unknown origin) preincubated with compound for 10 mins followed by DNA and NAD+ addition and measured after 60 mins by chemilumi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP2 in PARP1 knockout human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by sel...More data for this Ligand-Target Pair
Affinity DataEC50: 4.33E+3nMAssay Description:Binding affinity to PARP2 (unknown origin) assessed as DNA trapping activity incubated for 1 hr by Envision 2105 plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of PARP2 in PARP1 knockout human A549 cells preincubated with compound for 1 hr followed by H2O2 addition and measured after 5 mins by sel...More data for this Ligand-Target Pair
