Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50023597
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665623BDBM50665623(CHEMBL6176840)
Affinity DataIC50: 34nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665625BDBM50665625(CHEMBL6170310)
Affinity DataIC50: 40nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665624BDBM50665624(CHEMBL6174467)
Affinity DataIC50: 51nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665627BDBM50665627(CHEMBL6170180)
Affinity DataIC50: 58nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665626BDBM50665626(CHEMBL6152557)
Affinity DataIC50: 59nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665628BDBM50665628(CHEMBL6176476)
Affinity DataIC50: 59nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665628BDBM50665628(CHEMBL6176476)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665624BDBM50665624(CHEMBL6174467)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665625BDBM50665625(CHEMBL6170310)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665626BDBM50665626(CHEMBL6152557)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665627BDBM50665627(CHEMBL6170180)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665623BDBM50665623(CHEMBL6176840)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed