Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50023611
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 0.630nMAssay Description:Binding affinity to wildtype mouse STING incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to human STING AQ variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 1.90nMAssay Description:Binding affinity to His-tagged human STING CTD assessed as dissociation rate constant (Kd) by SPR analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Binding affinity to wildtype human STING R232 variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to His-tagged human STING CTD assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 24nMAssay Description:Binding affinity to His-tagged human STING CTD assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 330nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 740nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 980nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 1.02E+3nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 1.76E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity to wildtype mouse STING incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.61E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.51E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.66E+3nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 3.83E+3nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 4.02E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 4.19E+3nMAssay Description:Binding affinity to human STING H232 variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 4.66E+3nMAssay Description:Binding affinity to wildtype human STING R232 variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 5.68E+3nMAssay Description:Binding affinity to His-tagged human STING H232 variant assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 5.95E+3nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 6.33E+3nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 6.43E+3nMAssay Description:Binding affinity to His-tagged human STING H232 variant assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 8.26E+3nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 8.56E+3nMAssay Description:Binding affinity to His-tagged human STING CTD assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 8.92E+3nMAssay Description:Binding affinity to human STING AQ variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Binding affinity to human STING H232 variant incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 1.06E+4nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells expressing IRF inducible lucia luciferase gene under the control of ISG54 assessed ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataKd: 1.22E+4nMAssay Description:Binding affinity to His-tagged human STING CTD assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.05E+4nMAssay Description:Potentiation of cGAMP-induced STING pathway activation in human THP1-Dual KI-hSTING-R232 cells incubated for 24 hrs in presence of 5 microg/ml cGAMP ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.52E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataEC50: 2.70E+4nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells expressing SEAP gene assessed as NF-kappaB response incubated for 24 hrs by QUANTI-...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 3.38E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 4.15E+4nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Beijing Institute of Pharmacology & Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair




















