Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50023751
LigandChemical structure of BindingDB Monomer ID 50521215BDBM50521215(CHEMBL4435246)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataKi:  6.10nMAssay Description:Binding affinity to KEAP1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519234BDBM50519234(CHEMBL4440989)
Affinity DataKi:  13nMAssay Description:Binding affinity to KEAP1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575930BDBM50575930(CHEMBL4860934)
Affinity DataKi:  40nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) assessed as inhibition constant by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521220BDBM50521220(CHEMBL4476588)
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50522164BDBM50522164(CHEMBL4436827)
Affinity DataIC50: 160nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50667736BDBM50667736(CHEMBL6190292)
Affinity DataIC50: 250nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521220BDBM50521220(CHEMBL4476588)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521215BDBM50521215(CHEMBL4435246)
Affinity DataIC50: 630nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50667736BDBM50667736(CHEMBL6190292)
Affinity DataIC50: 790nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50522164BDBM50522164(CHEMBL4436827)
Affinity DataIC50: 790nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521215BDBM50521215(CHEMBL4435246)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521215BDBM50521215(CHEMBL4435246)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575918BDBM50575918(CHEMBL4867889)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to KEAP1 (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521220BDBM50521220(CHEMBL4476588)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50522164BDBM50522164(CHEMBL4436827)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50667736BDBM50667736(CHEMBL6190292)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50522164BDBM50522164(CHEMBL4436827)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575924BDBM50575924(CHEMBL4865680)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521220BDBM50521220(CHEMBL4476588)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575918BDBM50575918(CHEMBL4867889)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to KEAP1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521213BDBM50521213(CHEMBL4580395)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50667736BDBM50667736(CHEMBL6190292)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575924BDBM50575924(CHEMBL4865680)
Affinity DataKi:  1.56E+4nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) assessed as inhibition constant by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521213BDBM50521213(CHEMBL4580395)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521213BDBM50521213(CHEMBL4580395)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521213BDBM50521213(CHEMBL4580395)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521211BDBM50521211(CHEMBL4590704)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521211BDBM50521211(CHEMBL4590704)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521211BDBM50521211(CHEMBL4590704)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50521211BDBM50521211(CHEMBL4590704)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed