Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 6773
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152418BDBM152418((1E,1’E)-O,O’-(Ethane-1,2-diyl)bis[2,4,5...)
Affinity DataKi:  1.00E+3nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152420BDBM152420((E)-2,4,5-Trihydroxybenzaldehyde oxime (7))
Affinity DataKi:  2.60E+3nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152421BDBM152421((E)-2,4,5-Trihydroxybenzaldehyde O-methyl oxime (8...)
Affinity DataKi:  3.90E+3nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152422BDBM152422((E)-2,4,5-Trihydroxybenzaldehyde O-benzyl oxime (9...)
Affinity DataKi:  9.10E+3nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152434BDBM152434((E)-2-Fluoro-4,5-dihydroxybenzaldehyde O-methyl ox...)
Affinity DataKi:  1.51E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152417BDBM152417(Sodium (1E,7E)-1-(2,4,5-trihydroxyphenyl)-3,6-diox...)
Affinity DataKi:  1.84E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152429BDBM152429((E)-3,4,5-Trihydroxybenzaldehyde O-methyl oxime (1...)
Affinity DataKi:  2.94E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152433BDBM152433((E)-2-Hydroxy-3-nitrobenzaldehyde O-methyl oxime (...)
Affinity DataKi:  4.78E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152423BDBM152423(5-[(Methoxyamino)methyl]benzene-1,2,4-triol hydroc...)
Affinity DataKi: >7.50E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152424BDBM152424((E)-5-[(2-Methylhydrazono)methyl]benzene-1,2,4-tri...)
Affinity DataKi: >7.50E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152419BDBM152419(2,4,5-trihydroxybenzaldehyde (6))
Affinity DataKi: >7.50E+4nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152425BDBM152425((E,Z)-2,4,5-Trimethoxybenzaldehyde O-methyl oxime ...)
Affinity DataKi: >1.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152436BDBM152436((E)-2-Fluoro-4,5-dimethoxybenzaldehyde O-methyl ox...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152432BDBM152432((E)-4-Hydroxy-3-nitrobenzaldehyde O-methyl oxime (...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152435BDBM152435((E)-4,5-Difluoro-2-hydroxybenzaldehyde O-methyl ox...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152428BDBM152428((E)-2,4-Dihydroxybenzaldehyde O-methyl oxime (16))
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152430BDBM152430((E)-3,4-Dihydroxy-5-methoxybenzaldehyde O-methyl o...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152431BDBM152431((E)-Uracil-6-carbaldehyde O-methyl oxime (19))
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 50149225BDBM50149225(3,4-Dihydroxy-benzaldehyde O-methyl-oxime | CHEMBL...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152426BDBM152426((E)-2-Hydroxybenzaldehyde O-methyl oxime (14))
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandChemical structure of BindingDB Monomer ID 152427BDBM152427((E)-2,5-Dihydroxybenzaldehyde O-methyl oxime (15))
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed