Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50000054
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using midazolam as substrate preincubated with compound followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C19 using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C9 using diclofenac as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2B6 using bupropion as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2A6 using coumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP1A2 using phenacetin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrate preincubated with compound followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50239781(CHEMBL4066936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP2C8 using amodiaquine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed