Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50001246
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273514BDBM50273514(CHEMBL4127259)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273505BDBM50273505(CHEMBL4126712)
Affinity DataIC50: 36nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273513BDBM50273513(CHEMBL4127942)
Affinity DataIC50: 53nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273516BDBM50273516(CHEMBL4126967)
Affinity DataIC50: 65nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273515BDBM50273515(CHEMBL4128643)
Affinity DataIC50: 92nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273506BDBM50273506(CHEMBL4126552)
Affinity DataIC50: 109nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273517BDBM50273517(CHEMBL4128448)
Affinity DataIC50: 126nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273501BDBM50273501(CHEMBL4128910)
Affinity DataIC50: 155nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273503BDBM50273503(CHEMBL4130122)
Affinity DataIC50: 166nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273504BDBM50273504(CHEMBL4129976)
Affinity DataIC50: 192nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273518BDBM50273518(CHEMBL4127512)
Affinity DataIC50: 275nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273502BDBM50273502(CHEMBL4128759)
Affinity DataIC50: 335nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed