Compile Data Set for Download or QSAR
maximum 50k data
Found 126 Enz. Inhib. hit(s) with all data for entry = 50001638
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289534(CHEMBL2018574)
Affinity DataEC50:  5.90E+3nMAssay Description:Potentiator activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289535(CHEMBL4176184)
Affinity DataEC50:  1.60E+4nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289702(CHEMBL3746059)
Affinity DataEC50:  1.40E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289534(CHEMBL2018574)
Affinity DataEC50:  1.50E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataEC50:  2.60E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289704(CHEMBL260775)
Affinity DataEC50: <3.00E+3nMAssay Description:Corrector activity at human CFTR F508-del mutant expressed in rat FTR cells harboring YFP-H148Q/I152L preincubated for 18 to 24 hrs followed by forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  2.82E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289706(CHEMBL1257047)
Affinity DataEC50:  2.19E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289704(CHEMBL260775)
Affinity DataEC50:  1.10E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataEC50:  2.57E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289707(CHEMBL4170223)
Affinity DataEC50:  2.20E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289708(CHEMBL4174717)
Affinity DataEC50:  8.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289709(CHEMBL4166815)
Affinity DataEC50:  4.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289710(CHEMBL4171265)
Affinity DataEC50:  1.70E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289711(CHEMBL4163361)
Affinity DataEC50:  1.30E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289712(CHEMBL4167920)
Affinity DataEC50:  5.40E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289755(CHEMBL4160001)
Affinity DataEC50:  3.80E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289764(CHEMBL4162319)
Affinity DataEC50:  2.90E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289771(CHEMBL4167675)
Affinity DataEC50: >5.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289773(CHEMBL4169748)
Affinity DataEC50:  900nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289774(CHEMBL4161828)
Affinity DataEC50:  1.60E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289779(CHEMBL4166332)
Affinity DataEC50:  2.30E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289853(CHEMBL4176955)
Affinity DataEC50:  1.90E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289854(CHEMBL4162876)
Affinity DataEC50:  2.90E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289855(CHEMBL4173592)
Affinity DataEC50:  900nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289856(CHEMBL4159515)
Affinity DataEC50:  550nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289857(CHEMBL4170137)
Affinity DataEC50:  300nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289858(CHEMBL4164907)
Affinity DataEC50:  87nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289535(CHEMBL4176184)
Affinity DataEC50:  7.90E+3nMAssay Description:Potentiator activity at CFTR F508-del mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289859(CHEMBL2018581)
Affinity DataEC50:  1.51E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289860(CHEMBL2018582)
Affinity DataEC50:  6.76E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289861(CHEMBL2018583)
Affinity DataEC50:  2.69E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289862(CHEMBL2018585)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289863(CHEMBL1882863)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289864(CHEMBL1870726)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289865(CHEMBL2018587)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289866(CHEMBL2018588)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289867(CHEMBL1867725)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289868(CHEMBL2018590)
Affinity DataEC50:  4.27E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289869(CHEMBL2018591)
Affinity DataEC50:  1.00E+5nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289958(CHEMBL2018592)
Affinity DataEC50:  3.02E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289959(CHEMBL2018593)
Affinity DataEC50:  1.32E+4nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289960(CHEMBL4170164)
Affinity DataEC50:  8.51E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289962(CHEMBL1098166)
Affinity DataEC50:  3.39E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289965(CHEMBL4166758)
Affinity DataEC50:  933nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289966(CHEMBL4163314)
Affinity DataEC50:  759nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289967(CHEMBL4167860)
Affinity DataEC50:  1.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50290023(CHEMBL4159943)
Affinity DataEC50:  1.00E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289858(CHEMBL4164907)
Affinity DataEC50:  87nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289857(CHEMBL4170137)
Affinity DataEC50:  302nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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