Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50002412
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335557BDBM50335557(N,N-dipropyl-N'-[4-({[(1H-imidazol-2-yl)methyl][(1...)
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]SDF-1alpha from CXCR4 (unknown origin) expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458294BDBM50458294(CHEMBL4210165)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458281BDBM50458281(CHEMBL4217502)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074178BDBM50074178((1-Methyl-1-phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]tria...)
Affinity DataIC50: 7nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458283BDBM50458283(CHEMBL4212661)
Affinity DataIC50: 7nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458290BDBM50458290(CHEMBL4215051)
Affinity DataIC50: 7nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074167BDBM50074167(Phenethyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458288BDBM50458288(CHEMBL4218006)
Affinity DataIC50: 11nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458286BDBM50458286(CHEMBL2367715)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]SDF-1alpha from CXCR4 in human MT4 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458287BDBM50458287(CHEMBL4213081)
Affinity DataIC50: 15nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458297BDBM50458297(CHEMBL4213087)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458292BDBM50458292(CHEMBL4218011)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458293BDBM50458293(CHEMBL4205801)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458279BDBM50458279(CHEMBL4206706)
Affinity DataIC50: 27nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155310BDBM50155310(CHEMBL3779982)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]SDF-1 from human CXCR4 expressed in HEK293 cell membranes after 1.5 hrs by Topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458280BDBM50458280(CHEMBL4208687)
Affinity DataIC50: 150nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458289BDBM50458289(CHEMBL4213624)
Affinity DataIC50: 200nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458295BDBM50458295(CHEMBL4207733)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458285BDBM50458285(CHEMBL4202860)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458296BDBM50458296(CHEMBL4207204)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458277BDBM50458277(CHEMBL4212087)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458284BDBM50458284(CHEMBL4211557)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458282BDBM50458282(CHEMBL4216535)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458291BDBM50458291(CHEMBL4203386)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SDF-1 binding to CXCR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458278BDBM50458278(CHEMBL578702 | GNF-Pf-2242)
Affinity DataIC50: 2.16E+3nMAssay Description:Displacement of [125I]SDF-1 from human CXCR4 expressed in HEK293 cell membranes after 1.5 hrs by Topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed