Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50006896
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055122BDBM50055122(bicyclic N-hydroxy urea derivatives | CHEMBL358775)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055118BDBM50055118(N-Hydroxy-N-[1,2,3,4-tetrahydro-6-((4-methoxy)benz...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055127BDBM50055127(bicyclic N-hydroxy urea derivatives | CHEMBL148298)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055142BDBM50055142(bicyclic N-hydroxy urea derivatives | CHEMBL148096)
Affinity DataIC50: 520nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055119BDBM50055119(bicyclic N-hydroxy urea derivatives | CHEMBL344114)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055143BDBM50055143(bicyclic N-hydroxy urea derivatives | CHEMBL149384)
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055126BDBM50055126(N-Hydroxy-N-[2,3-dihydro-5-(benzyloxy)-1H-inden-1y...)
Affinity DataIC50: 780nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055125BDBM50055125(N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(phenoxy)-1-naph...)
Affinity DataIC50: 840nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055128BDBM50055128(N-Hydroxy-N-[2,3-dihydro-5-(phenoxy)-1H-inden-1yl]...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055126BDBM50055126(N-Hydroxy-N-[2,3-dihydro-5-(benzyloxy)-1H-inden-1y...)
Affinity DataIC50: 880nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055136BDBM50055136(N-Hydroxy-N-[1,2,3,4-tetrahydro-5-(benzyloxy)-1-na...)
Affinity DataIC50: 910nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055139BDBM50055139(N-Hydroxy-N-[1,2,3,4-tetrahydro-7-(benzyloxy)-1-na...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055134BDBM50055134(bicyclic N-hydroxy urea derivatives | CHEMBL148844)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055115BDBM50055115(1-(6-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-1-yl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055115BDBM50055115(1-(6-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-1-yl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055132BDBM50055132(N-Hydroxy-N-[2,3-dihydro-5-(4-methoxy benzyloxy)-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055131BDBM50055131(bicyclic N-hydroxy urea derivatives | CHEMBL422666)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055141BDBM50055141(bicyclic N-hydroxy urea derivatives | CHEMBL346172)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055133BDBM50055133(N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(4-chlorobenzylo...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055120BDBM50055120((-)-N-Hydroxy-N-[2,3-dihydro-6-(benzyloxy)benzofur...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055120BDBM50055120((-)-N-Hydroxy-N-[2,3-dihydro-6-(benzyloxy)benzofur...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055121BDBM50055121(N-Hydroxy-N-[2,3-dihydro-6-(4-methoxy benzyloxy)be...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055129BDBM50055129(N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(phenyl)-1-napht...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055117BDBM50055117(N-Hydroxy-N-[2,3-dihydro-6-(phenoxy)benzofuran-3-y...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055124BDBM50055124(N-Hydroxy-N-[2,3-dihydro-7-(benzyloxy)benzofuran-3...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055140BDBM50055140(bicyclic N-hydroxy urea derivatives | CHEMBL424122)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055135BDBM50055135(bicyclic N-hydroxy urea derivatives | CHEMBL343008)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055123BDBM50055123(N-Hydroxy-N-[2,3-dihydro-7-(phenoxy)-1H-inden-1yl]...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055130BDBM50055130(bicyclic N-hydroxy urea derivatives | CHEMBL145933)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055137BDBM50055137(bicyclic N-hydroxy urea derivatives | CHEMBL149926)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055138BDBM50055138(N-Hydroxy-N-[1,2,3,4-tetrahydro-1-naphthalenyl]ure...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055116BDBM50055116(N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(methoxy)-1-naph...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed