Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50007185
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50158345(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3...)
Affinity DataEC50:  13nMAssay Description:Inhibition of S1P1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50507186(Ozanimod | RPC-1063 | RPC1063)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) assessed as reduction in forskolin-induced cAMP accumulation after 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50507187(CHEMBL4579553)
Affinity DataEC50:  1.20nMAssay Description:Activation of human recombinant S1P1 expressed in CHO cell membranes after 120 mins by GTP-gamma-35S-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50507186(Ozanimod | RPC-1063 | RPC1063)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) after 120 mins in presence of [35S]-GTPgammaS by Topcount methodMore data for this Ligand-Target Pair