Found 17 Enz. Inhib. hit(s) with all data for entry = 50010741 TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 276nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Federal University Of Rio De Janeiro (Ufrj)
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
